Best of the old Fallouts, best of the Brotherhood of Steel.
Hopefully the talk about Chicago in Fallout 3 and Fallout: New Vegas means we'll be going back there. Maybe we'll meet the Warrior... or at least his or her family, and perhaps use the armor and weapons he or she used. Super Mutants that brandished M2 Brownings as if they were pistols and fired deadly hails of Depleted Uranium, in 15-round burst mode, with Sniper-like accuracy, were destroyed by the Warrior and his squad. Biggest Goddamn Hero of the Wasteland, in my opinion.
I didn't HATE it. But it definitely could have been better. The power armor DID look cool, BUT it made no sense. The Brotherhood didn't have the proper equipment to make newer, more advanced power armor. That was established in the first two games. Tactics also seemed to use concept designs for super mutants, deathclaws, etc. instead of the designs that were actually implemented in the other games.
Also, you can say the Deathclaws in the Midwest simply mutated differently. But I think the Super Mutants were explicitly stated to be remnants of the Master's army, so I can't think of any justification for their oddness.